Misfortune is one of those cards players keep asking about. Here is, in plain words, what its official text says, the rulings published by Wizards of the Coast, and the combos players actually run.

Official card text

An opponent chooses one — • You put a +1/+1 counter on each creature you control and gain 4 life. • You put a -1/-1 counter on each creature that player controls and Misfortune deals 4 damage to that player.

How it works : Misfortune

Original English text — Wizards of the Coast / Scryfall

No additional ruling has been published for this card.

Interactions with other cards

These cards' text mentions Misfortune.

Wheel of Misfortune

Each player secretly chooses a number 0 or greater, then all players reveal those numbers simultaneously and determine the highest and lowest numbers revealed this way. Wheel of Misfortune deals damage equal to the highest number to each player who chose that number. Each player who didn't choose the lowest number discards their hand, then draws seven cards.