Sign in Blood is one of those cards players keep asking about. Here is, in plain words, what its official text says, the rulings published by Wizards of the Coast, and the combos players actually run.
Official card text
Target player draws two cards and loses 2 life.
Complete guide
Sign in Blood is a classic black sorcery that embodies the philosophy of power at any cost. By trading a small portion of your life force, you gain immediate access to the resources needed to dominate the game. This card is a staple for players who aren't afraid to bleed for an advantage.
What It Does
At its core, Sign in Blood is a card-draw spell that targets a player. That player draws two cards and subsequently loses 2 life. Because it specifies 'target player,' you can use it on yourself to refill your hand or on an opponent to deal the final two points of damage needed to win the game.
How It Resolves
When you cast the spell, you first choose a target player. Upon resolution, the targeted player draws two cards from their library. Immediately after the cards are drawn, that same player loses 2 life. This loss of life is not damage, so it cannot be prevented by effects that prevent damage.
Common Mistakes
A frequent error is forgetting that the life loss is mandatory and part of the resolution; if you are at 2 or less life, casting this on yourself will cause you to lose the game. Additionally, remember that this is a Sorcery, meaning it can only be cast during your main phase when the stack is empty, unlike Instant-speed draw spells.
When to Play It
The best time to play Sign in Blood is when you need to dig for specific answers or land drops. Since it costs two black mana, it is most effective in decks with a heavy black mana base. Use it early to keep your momentum or late to finish off a weakened opponent.
Interaction examples
First, you cast Sign in Blood on yourself to draw two cards, potentially putting a powerful creature into your hand. If you have already exceeded your hand size, you might discard that creature at the end of the turn. Then, you can cast Reanimate to bring that creature back to the battlefield, though you must be careful as both spells will cost you a significant amount of life.
If you are looking for a specific combo piece, you can cast Demonic Tutor to search your library for Sign in Blood. After putting it in your hand and shuffling, you cast Sign in Blood to draw two additional cards. This sequence allows you to thin your deck and maximize your chances of finding exactly what you need to win.
Guide written with AI from the official text and rulings. Official English text prevails.
How it works : Sign in Blood
Original English text — Wizards of the Coast / Scryfall
No additional ruling has been published for this card.
Legal formats
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Meta decks with Sign in Blood
No archived Top 8 deck with this card yet.



Reanimate
Demonic Tutor