Witness the End — ruling 1

If that player has only one card in hand, that card will be exiled. If the player has no cards in hand, no cards will be exiled, but they will still lose 2 life.

Witness the End : règles, fonctionnement et interactions (MTG)

Witness the End is one of those cards players keep asking about. Here is, in plain words, what its official text says, the rulings published by Wizards of the Coast, and the combos players actually run.

Official card text

Devoid (This card has no color.) Target opponent exiles two cards from their hand and loses 2 life.

How it works : Witness the End

Original English text — Wizards of the Coast / Scryfall

#1January 22, 2016· Wizards of the Coast
If that player has only one card in hand, that card will be exiled. If the player has no cards in hand, no cards will be exiled, but they will still lose 2 life.
No other card is named in this ruling.