Dissection Practice is one of those cards players keep asking about. Here is, in plain words, what its official text says, the rulings published by Wizards of the Coast, and the combos players actually run.
Official card text
Target opponent loses 1 life and you gain 1 life. Up to one target creature gets +1/+1 until end of turn. Up to one target creature gets -1/-1 until end of turn.
Complete guide
Dissection Practice is a versatile black instant that offers a triple threat of effects for a very low mana cost. It allows you to drain your opponent's life while simultaneously shifting the balance of power on the battlefield. Whether you need to push through extra damage or eliminate a pesky small creature, this spell provides the surgical precision required.
A Multipurpose Tool
Dissection Practice has three distinct effects. First, it causes a target opponent to lose 1 life and gives you 1 life. Second, it allows you to give a creature +1/+1 until end of turn. Finally, it allows you to give a creature -1/-1 until end of turn. Because the creature-targeting effects use the phrase "up to one," you can cast this spell even if there are no creatures on the battlefield, or if you only want to affect one creature instead of two.
Resolution Step-by-Step
When you cast Dissection Practice, you choose your targets: one opponent, zero or one creature for the buff, and zero or one creature for the debuff. Upon resolution, the game checks if the targets are still legal. If the targeted opponent is the only target and they gain hexproof, the spell is removed from the stack. If at least one target remains legal, the spell resolves as follows: the opponent loses 1 life, you gain 1 life, then the chosen creatures receive their respective power and toughness modifications. If a creature was targeted to receive -1/-1 and its toughness becomes 0, it is put into the graveyard as a state-based action after the spell finishes resolving.
Strategic Timing
As an instant, Dissection Practice is most effective during the combat phase. You can use it to save one of your attackers from a blocker, or to weaken an opponent's blocker so your creature survives. It can also be used in response to damage spells to keep a vital creature alive. Remember that the life drain targets an opponent, so it can be used to finish off a player who is at exactly 1 life.
Common Mistakes
One common error is forgetting that you must choose an opponent to target; the spell cannot be cast if your opponent has protection from black or hexproof and there are no other opponents. Additionally, players sometimes forget that the same creature can be targeted by both the +1/+1 and the -1/-1 effects, which would result in a net change of 0/0, though this is rarely beneficial.
Interaction examples
On turn one, you cast Dark Ritual to add three black mana to your pool. You use one mana to cast a small creature and another mana to cast Dissection Practice. You target your opponent for the life drain and your own creature for the +1/+1. This allows you to attack for increased damage immediately while padding your own life total, all while still having one mana left in your pool.
During your opponent's end step, you cast Vampiric Tutor, searching for a card and losing 2 life. On your turn, you cast Dissection Practice targeting your opponent. The 1 life you gain from Dissection Practice helps mitigate the life loss from the Tutor, while the -1/-1 effect can be used to pick off a small utility creature your opponent just played.
During combat, your 2/2 creature is blocked by an opponent's 2/2 creature. You cast Dissection Practice, targeting your creature with +1/+1 and their creature with -1/-1. Your creature becomes a 3/3 and their creature becomes a 1/1. Your creature survives the combat, theirs is destroyed, and you gain 1 life while they lose 1 life.
Guide written with AI from the official text and rulings. Official English text prevails.
How it works : Dissection Practice
Original English text — Wizards of the Coast / Scryfall
No additional ruling has been published for this card.
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Meta decks with Dissection Practice
No archived Top 8 deck with this card yet.



Dark Ritual
Vampiric Tutor